Building a Kick-Ass Immune System
We have surely entered an interesting time...
First-- a sudden rush of panic. A massive push to wash hands. Cover your projectable excretions. Self-quarantine if experiencing any symptoms...
Similar to advice given during normal flu
Then schools started closing.
Then it was suggested that anyone that 'could' work from home.. should.
More and more news reports coming in from around the globe (or more like.. a handful of places) of overwhelmed hospitals and absolute carnage.. everywhere.
The chaos escalates, uncertainty accumulates, and the FEAR settles in amongst the general public.
If I would have told you 6 months ago-- the entire globe is going to completely shut down due to speculations of a deadly pandemic.. you would have called me a lunatic.
But-- Let's just focus on the CONTROLLABLE for now.
Yes, that means what YOU can be doing right now.
“Your immune system is a muscle.” – Dr. Jockers
-->MaxLiving
A robust immune system will convey good overall health
-->Not just a defense against all the 'germs' floating around
It's about building RESILIENCY so that your body and it's amazing systems can ADAPT and handle various stressors and 'invadors' that come along.
It's meant to.
You just need to give it the chance to.
The Basics
Year, after year... after year. Who is it that's at the highest risk of serious complications when it comes to having the flu? Or .. whatever virus happens to be circling the planet at any particular moment?
--> Immunocomprimised, elderly, those dealing with multiple conditions.
What types of lifestyle choices are ALWAYS mentioned when it comes to putting people at higher risk?
-->
Let's break those down
Here's your list to CREATE a titanium immune system!
Each is covered in more detail below.
- Nutrition
- What you Eat Matters
- Supplements?
- Healthy Gut
- Your gut is your primary hub for your immune system-- treat it right!
- Optimize Nervous System
- Proper spinal alignment
- Proper Posture
- Spinal movement
- MOVE
- Genetic requirement
- Detoxifying
- Mindset|Meditation|Stress|Sleep
What does this look like?
First of all-- You are DESIGNED and equipped to handle 'invaders' or pathogens. Every. Single. Day. Everywhere you go. Every breath of air. Every single thing you touch. Taste. EVERYTHING has 'GERMS'. If these 'germs' were to blame for Luckily--You have many lines of defense that keep you healthy.
- Regular aerobic exercise
- curcumin
- Resveratrol
- Rosmary and oregano
- ALA
- Ginseng
"There's a community of 38,000,000,000,000 microorganisms (mostly bacteria) living in and on us. Seededby our mothers, this is our microbiome—our non-human half we can’t live without. In an astonishing journey of symbiosis, microbes co-evolved with us, carrying in their genes, and therefore in us, the entire history of the world" -seed.com
What about Fevers?
<<They're NOT a mistake!!>>
This is your body's natural, adaptive response.. and a pathogen (unwanted invader)
- For 600 million years warm and cold blooded animals have utilized fevers (how they were able to determine this.. is beyond me!)
- A vast, dynamic orchestrated response that requires proper signaling between the immune system and nervous system.
- Requires LOTS of energy and resources:
- 1 deg C raise in temp==10-12.5% inc in metabolic rate!!
- For example, temperatures in the febrile range (40–41°C) cause a greater than 200-fold reduction in the replication rate of poliovirus in mammalian cells and increase the susceptibility of Gram-negative bacteria to serum-induced lysis.24,25
- "There is mounting evidence that the increase of 1 to 4°C in core body temperature that occurs during fever is associated with improved survival and resolution of many infections. For example, the use of antipyretic drugs to diminish fever correlates with a 5% increase in mortality in human populations infected with influenza virus and negatively affects patient outcomes in the intensive care unit.3–5"
- Some studies have shown that in cases where inflammation inflammatory
The latest:
Literature review from 2019:
"Conclusion: the evidence does not currently support routine antipyretic administration."
You can't mess with mother nature.. and not expect any repercussions.
Scurvy:
"Must be a demon."
-->Orrrr... complete void of any fresh foods with vitamin C.
Pollegra: Must have been the Italians coming in by sea and bringing something in with them..."
Nope.. it's a deficiency in Niacin.
Picture this: Classroom of kids
Fever and the thermal regulation of immunity: the immune system feels the heat
Obviously.. there's a time and place.
330,000,000 Americans
According to this study/ article, 20,000,000+ children and teens are on prescription drugs, 41,250,000 men take some sort of prescription drug, approximately 54,000,000 women , and almost 62,000,000 seniors take prescriptions! (Assuming 1/4 of the population per category)
Nutrition
No better time to get healthy than... NOW!
YES. What we consume everyday affects EVERY system of our body... including our Immune system!!
The best part is... the same things you would do to create a robust, resilient immune system--- are the same, or very similar to, the things you would do to prevent (and even reverse!) heart disease, diabetes, neurological conditions, cancer, autoimmune conditions, gut issues, chronic fatigue, thyroid dysfunction, sleep problems, etc etc. Now.. there are stipulations to each of these-- but regardless of what condition we're talking about, what you fuel your body with day in, and day out will ultimately affect your overall expression of health.
You can have a positive effect.. or negative. The choice is yours!
The truth is.. we've create the perfect storm in terms of creating the perfect environment in which disease can initiate.. and thrive. A pleathora of toxic-processed junk foods, an absurd amount of sugar/carbs, low quality animal products, and chemicals that are used in the food production process ALL have an effect on our physiology. All of which lead to dysfunction to some degree. After enough time.. dysfunction leads to an inability for your body to adapt-- and 'symptoms' surface.
Fast food fever: reviewing the impacts of the Western diet on immunity
"The Western diet is characterized by a high intake of saturated and omega-6 fatty acids, reduced omega-3 fat intake, an overuse of salt, and too much refined sugar [1]. Most are aware that this type of eating, if not in moderation, can damage the heart, kidneys, and waistlines; however, it is becoming increasingly clear that the modern diet also damages the immune system."
--> Which, the immune system is further stressed by .. stress. Lack of sleep. Pollution and toxins. Lack of sunlight. Lack of movement. Etc.
Obese individuals have fewer white blood cells to fight infection and those cells they do possess have reduced phagocytosis capability [11,12]
COVID-19 and metabolic syndrome: could diet be the key?
Towards a Food Pharmacy: Immunologic Modulation through Diet
Citrus Fruits
https://beatingsugaraddiction.com/health-benefits-of-citrus/
Supplementation?
It all starts with your diet... you can't out-supplement a horrid diet.
But-- there are certain things that DO make a significant difference.. and are great to incorporate on a normal basis!
The basics
- Vitamin C: 3,000 mg - 5,000 mg (or more) daily, divided into 1,000mg doses.
- Liposomal forms will be best absorbed/utilized
- Vitamin D3: 1000 IUs for every 35-100 lbs of body weight. (Depending on who you talk to.. but Roughly-- 3000 to 6000 IUs for most.
- Most will require closer to 5,000 IUs/day.
- Best source? The SUN.
- Older adults do not create their own as easily.
- K2, and Magnesium are important to properly convert.
- Magnesium: 400 mg daily (in the form of citrate, malate, chelate, or glycinate)
- Zinc: 30 mg daily
- Selenium: 100 mcg (micrograms) daily
- Other alkalizing trace minerals
- Ionized trace mineral supplements (pour into water). 1/2 tsp per glass of water.
- Celtic sea salt. Himalayan salt.
If getting sick:
GOOD! You getting 'sick' is just an effect of your body reacting and neutralizing unwanted pathogens. Your body is designed to raise it's temperature and release specialized immune cells to initiate an inflammatory response. Which, is later counteracted by it's own innate ability to produce an anti-inflammatory response. During these phases, your body may (or may not-depending on the severity of the response)-- produce 'symptoms'. Again.. these are GOOD. Suppressing these will only elongate the process, or create other issues down the road. SUPPORTING your body and immune system is a different story. There are various things we can do to help with these processes!
- Stay CALM
- Stress will only make matters worse! Trust in your body. Be at peace. Let the HEALING commence.
- Incorporate peaceful and destressing
- Bump Vit D intake to 20-50K IUs for a few days, then back down to 5-10K.
- 1000 mg Vit C every 2-3 hours, or as your GI system can handle it.
- Quercitin
- Vitamin A: Cod Liver oil is a GREAT bioavailable source.
Many herbs and spices have immune modulating/enhancing abilities. Whether it's through the activation of various immune factors endogenously, or, through anti-viral/bacterial properties.. utilizing herbs and Spices is a simple, effective, AND tasty way to improve your immune system (and overall health!)
- Oregano
- Echinacea
- Turmeric
- Ginger
- Garlic
- Mushrooms
- Reishi, Cordyceps
- Clove
- Lemon
- Medium Chain Triglycerides (MCT)
- Butryic Acid
- Make a Tea
- Diffuse oils
- Make your own lotion, soap, hand sanitizer, mouthwash,
- Encapsulate oils, herbs, spices
|
- Turmeric
- Ginger
- Mushrooms
- Cinnamon
- MCT oil
Inadequacy of Immune Health Nutrients: Intakes in US Adults, the 2005–2016 NHANES
micronutrient usual intake estimates based on nationally representative data in 26,282 adults (>19 years) from the 2005–2016 National Health and Nutrition Examination Surveys (NHANES). Overall, the prevalence of inadequacy (% of population below estimated average requirement [EAR]) in four out of five key immune nutrients is substantial. Specifically, 45% of the U.S. population had a prevalence of inadequacy for vitamin A, 46% for vitamin C, 95% for vitamin D, 84% for vitamin E, and 15% for zinc
Lower zinc levels in the blood are associated with an increased risk of death in patients with COVID-19
Vitamin D
SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels
Studies suggest an association between vitamin D deficiency and risk of viral upper respiratory tract infections and mortality from coronavirus disease-2019 (COVID-19) [1, 2]. This relationship is anticipated, given that vitamin D has numerous actions affecting the innate and adaptive immune systems. Respiratory monocytes/macrophages and epithelial cells constitutively express the vitamin D receptor. Acting through this receptor, vitamin D may be important in protection against respiratory infections [3]. In addition, an important action of vitamin D is suppressing excessive cytokine release that can present as a “cytokine storm,” a common cause of COVID-19-related morbidity and mortality [4].
Melatonin
https://www.sciencedaily.com/releases/2020/11/201109152223.htm
Kaufman HW, Niles JK, Kroll MH, Bi C, Holick MF (2020) SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels. PLoS ONE 15(9): e0239252. https://doi.org/10.1371/journal.pone.0239252
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0239252&utm_campaign=Chris+Kresser+General+News&utm_medium=email&_hsmi=96001443&_hsenc=p2ANqtz-98CkItsXfZX6x9O15dXeg3SEdImuSb5-lOaqIIC8riChOGbLiTrCos7onFrRW7j4Vgamq5VIlv5TVbsGufapKrQPF7DQ&utm_content=96001443&utm_source=hs_email&fbclid=IwAR1ShGu17w0moUAFzoY25vfHVCE-iAiClBFXIKR8-xYuoLaCznv7WZKyjas
- Analysis of patient data from Cleveland Clinic's COVID-19 registry also revealed that melatonin usage was associated with a nearly 30 percent reduced likelihood of testing positive for SARS-CoV-2 (the virus that causes COVID-19) after adjusting for age, race, smoking history and various disease comorbidities. Notably, the reduced likelihood of testing positive for the virus increased from 30 to 52 percent for African Americans when adjusted for the same variables.
Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis
- Biocidin
- https://nutridyn.com/immune-health/biocidinr-capsules
- Complex of various immune system
- Bacticidix
- Elderberry-Ginger-Echinacea
- Colloidal Silver
- Collostrum
- Vitamin C
- Liposomal C
- Glutathione
- Zinc
- Beta Glucans
- Probiotics
- https://seed.com/
- Spore based
- Ancient nutrition
- Diverse
- Magnesium
- Go for high quality... not just rock salts
https://revelationhealth.com/collections/immune-support
- These components play important biological roles that are vital to proper health and immune function, including:
- Cytokines: Part of your systemic immune system. These messengers keep communication between immune cells active to regulate the body’s immune response
- Lactoferrin: Lactoferrin assists with iron absorption and is a crucial part of your immune defense system.
- Immunoglobulins: (IgA, IgD, IgE, IgG, IgM) Immunoglobulins are small proteins that are used by your immune system to seek out and destroy foreign antigens (invaders).
- Proline-Rich Polypeptides: PRPs are important immune system regulators that encourage the growth of white blood cells and may restore the balance of cellular immune functions. PRPs may defend against oxidative stress and support brain health.
Immune PRP Pro
Large 12-week study found that supplementing with garlic daily reduced the number of colds by 63%, when compared to a placebo.
Vitamin C intake and susceptibility to the common cold.
Adults: 10-20,000 IU daily
Children: 3-5000 IU daily
D3 activates your P53 gene which is responsible for DNA synthesis of your immune system.
Adults: 2-3,000mg daily
Children: 500-1,000mg daily
Vitamin C stimulates the production of white blood cells, especially lymphocytes which are antiviral.
- Plays a particular role in inflammation modulation:: Inhibits the release of histamines -- which can constrict the bronchi and bronchioles (the major airways into the lungs) .
Research evaluating the efficacy of zinc shows that it can interfere with a molecular process that causes bacteria buildup in the nasal passages.
Efficacy of zinc against common cold viruses: an overview.
Zinc for the common cold.
Zinc for the common cold.
Influenza Virus and Glycemic Variability in Diabetes: A Killer Combination?
"exposure of pulmonary epithelial cells to elevated glucose concentrations significantly increased influenza virus infection and replication (Kohio and Adamson, 2013), suggesting that hyperglycemia may increase viral replication in vivo. Elevated glucose levels may also serve to suppress the anti-viral immune response (Reading et al., 1998). In a mouse model of type I diabetes, susceptibility to influenza was associated with a reduction in the anti-viral activity of collectins (Reading et al., 1998). This immunosuppression was driven by hyperglycemia as disease susceptibility could be reversed with insulin treatment (Reading et al., 1998). These findings are consistent with studies of patients infected with highly pathogenic avian influenza, whereby hyperglycemia was associated with a fatal outcome (Wiwanitkit, 2008)."
"Finally, it is important to recognize that during influenza virus pandemics of the last century (including the 2009 H1N1 pandemic) the majority of fatalities were the result of secondary bacterial infections, rather than primary viral pneumonia (Short et al., 2012). Elevated airway glucose concentrations can increase the replication of respiratory bacterial pathogens (Garnett et al., '
"Glycemic variability is induced by many different factors including consuming a meal, changes in exercise, weight, medication, diet, and sleep patterns (Davies, 2004)"
"There is now a growing body of evidence showing that glycemic oscillations play an important role in endothelial dysfunction, irrespective of HbA1c levels (Risso et al., 2001; Quagliaro et al., 2003; Azuma et al., 2006; Ceriello et al., 2008)"
"Given that glycemic oscillations are known to induce endothelial cytokine production (Quagliaro et al., 2005; Mudaliar et al., 2014) and enhance the expression of endothelial adhesions (Quagliaro et al., 2005; Mudaliar et al., 2014), it is tempting to speculate that glycemic variability augments the severity of influenza, at least in part, via effects on pulmonary endothelial cells."
The Nervous System
"Contemporary research is beginning to shed light on the neurobiological mechanisms, which may explain the outstanding clinical results chiropractors have experienced when managing patients with viral and infectious diseases…. A comprehensive review of the research literature reveals the current understanding that the brain and immune system are the two major adaptive systems in the body. During an immune response, the brain and the immune system “talk to each other” and this process is essential for maintaining homeostasis, or balance in the body."
Your spine--
PERSPECTIVES ON CHIROPRACTIC AND IMMUNITY
"Chiropractors helping patients battle the flu is not a new occurrence. During the 1917–18 influenza epidemic, an estimated 20 million people died throughout the world, including about 500,000 Americans. It was chiropractic’s success in caring for flu victims that led to the profession’s licensure in many states. Researchers reported that in Davenport, Iowa, out of the 93,590 patients treated by medical doctors, there were 6,116 deaths— a loss of one patient out of every 15. Chiropractors at the Palmer School of Chiropractic in Davenport adjusted 1,635 cases of flu-stricken patients, with only one subsequent death. Outside Davenport, chiropractors in Iowa cared for 4,735 cases with only six deaths— one out of 866. During the same epidemic, in Oklahoma, out of 3,490 flu patients under chiropractic care, there were only 7 deaths. Furthermore, chiropractors were called in for 233 cases that were given up as lost by the medical establishment, and reportedly saved all but 25. In another report covering 4,193 cases by 213 chiropractors, 4,104 showed complete recovery."
“These results are not so surprising, given what we now know about the interaction between the nervous system and the immune system,” writes Matthew McCoy, D.C., M.P.H., editor of The Journal of Pediatric, Maternal & Family Health–Chiropractic. “Through research we know that chiropractic has beneficial effects on immunoglobulins, B-lymphocytes (white blood cells), pulmonary function and other immune system processes.” One such study, conducted by Patricia Brennan, Ph.D., and her team, found that when a chiropractic “manipulation” was applied to the middle back, the response of polymorphonuclear neutrophils (white blood cells) taken from blood collected 15 minutes after the manipulation was significantly higher than blood collected 15 minutes before the chiropractic procedure. This research demonstrated an “enhanced respiratory burst” following the chiropractic adjustment. This burst is needed for our immune cells to destroy invading viruses and bacteria.
Another small study was conducted to study the effects of specific chiropractic adjustments on the immune systems of HIV-positive individuals. Over the six-month period of the study, the group that did not receive chiropractic care experienced a 7.96 percent decrease in CD4 cell counts; the adjusted group experienced a 48 percent increase in CD4 cell counts over the same period.
It is important to note that chiropractic is not the treatment of conditions. Treating disease is the practice of medicine. What distinguishes chiropractic from medicine is its emphasis on restoring function to the body by enhancing the performance of the nervous system. Chiropractic restores the integrity of the nervous system. When a vertebra subluxates (misaligns and interferes with nerve impulses), it inhibits the body from functioning optimally and results in a loss of health. The chiropractor regularly checks the spine to correct subluxations soon after they occur. This is the uniqueness of chiropractic. It is a service that no one else performs and is a necessary component of restoring well-being, which is starkly different from a diseasetreating approach.
Additionally, chiropractors understand the importance of things like nutrition and lifestyle, which are often neglected in conventional healthcare.
http://www.ccr.life.edu/wp-content/uploads/2020/04/Immunity-Osteopathic-Reviews-and-Theory.pdf
The vagus nerve has an important role in regulation of metabolic homeostasis, and efferent vagus nerve-mediated cholinergic signalling controls immune function and proinflammatory responses via the inflammatory reflex. Dysregulation of metabolism and immune function in obesity are associated with chronic inflammation, a critical step in the pathogenesis of insulin resistance and type 2 diabetes mellitus. Cholinergic mechanisms within the inflammatory reflex have, in the past 2 years, been implicated in attenuating obesity-related inflammation and metabolic complications. This knowledge has led to the exploration of novel therapeutic approaches in the treatment of obesity-related disorders.
The sympathetic nerve--an integrative interface between two supersystems: the brain and the immune system.
Chiropractic Care Facilitates Immune Function
https://www.circleofdocs.com/chiropractic-care-facilitates-immune-function/?fbclid=IwAR2HlzmzeVYk7wrMF4NZDSEFhk6dYpeLKf0GV16zBJyap_lDcu7PdJbVnN8
PERSPECTIVES ON CHIROPRACTIC AND IMMUNITY
Neuroendocrine Interactions in the Immune System
The sympathetic nerve--an integrative interface between two supersystems: the brain and the immune system.
Fundamental aspects of neural-immune signaling.
The vagus nerve and the inflammatory reflex—linking immunity and metabolism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082307/pdf/nihms488460.pdf
Abstract
The vagus nerve has an important role in regulation of metabolic homeostasis, and efferent vagus nerve-mediated cholinergic signalling controls immune function and proinflammatory responses via the inflammatory reflex. Dysregulation of metabolism and immune function in obesity are associated with chronic inflammation, a critical step in the pathogenesis of insulin resistance and type 2 diabetes mellitus. Cholinergic mechanisms within the inflammatory reflex have, in the past 2 years, been implicated in attenuating obesity-related inflammation and metabolic complications. This knowledge has led to the exploration of novel therapeutic approaches in the treatment of obesity-related disorders.
The inflammatory reflex is a physiological mechanism through which the vagus nerve regulates immune function and inhibits excessive proinflammatory cytokine production ▪ Vagus nerve signalling has an important role in the regulation of feeding behaviour and metabolic homeostasis ▪ Disruption of metabolic and immune regulation in obesity results in inflammation, which mediates insulin resistance and the development of type 2 diabetes mellitus as well as other debilitating and life-threatening conditions ▪ Activation of cholinergic signalling in the efferent arm of the inflammatory reflex alleviates obesity-associated inflammation and metabolic derangements ▪ The inflammatory reflex can potentially be exploited for treatment of the metabolic syndrome, type 2 diabetes mellitus and other obesity-driven disorders
Enhancement of in vitrointerleukin-2 production in normal subjects following a single spinal manipulative treatment
Enhanced phagocytic cell respiratory burst induced by spinal manipulation: potential role of substance P.
Enhanced neutrophil respiratory burst as a biological marker for manipulation forces: duration of the effect and association with substance P and tumor necrosis factor.
The Effects Induced by Spinal Manipulative Therapy on the Immune and Endocrine Systems
The immunological case for staying active during the COVID-19 pandemic
Meds?
Known for quite some time that asprin/ibuprofen and their relatives-- inhibit the bodies natural production of certain immune system cells
Influenza vaccination and respiratory virus interference among Department of Defense personnel during the 2017–2018 influenza season
Immune Boosters: 12 Natural Immune System Modulators
https://drjockers.com/immune-boosters-modulators/
More on Fevers
Fever and the thermal regulation of immunity: the immune system feels the heat
The effect of antipyretic therapy upon outcomes in critically ill patients: a randomized, prospective study.
- "The study was stopped after the first interim analysis due to the mortality difference, related to the issues of waiver of consent and the mandate for minimal risk."
- "
CONCLUSIONS:
Aggressively treating fever in critically ill patients may lead to a higher mortality rate."
Antipyretic drugs in patients with fever and infection: literature review
- "https://www.researchgate.net/publication/333321731_Antipyretic_drugs_in_patients_with_fever_and_infection_Literature_review"
- Conclusion: the evidence does not currently support routine antipyretic administration.
Faster recovery and reduced paracetamol use – a meta-analysis of EPs 7630 in children with acute respiratory tract infections
https://store.maxliving.com/pages/coronavirus-prevention?utm_source=consumer-essentials&utm_medium=email&utm_campaign=0314520&utm_term=covid19
https://store.maxliving.com/pages/immune-boost-perspective?utm_source=consumer-essentials&utm_medium=email&utm_campaign=0314520&utm_term=immune_boost_persepective
How Sugar Affects The Immune System
More about herbs, spices etc
Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial
GERM THEORY
Bechamp or Pasteur
https://www.dominicanajournal.org/wp-content/files/old-journal-archive/vol9/no1/dominicanav9n1bechamporpasteur.pdf
Germ Theory Versus Terrain: The Wrong Side Won the Day
https://www.westonaprice.org/health-topics/notes-from-yesteryear/germ-theory-versus-terrain-the-wrong-side-won-the-day/Do We look at Virus' differently?
Dr. Andrew Kaufman
Exosomes
Dr. Thomas Cowan, MD at Healthy Immunity 2019
T-cells Are the Superstars in Fighting COVID-19 — But Why are some People So Poor at Making Them?
Eshani M King, Evidence Based Research in Immunology and Health
Covid-19: Do many people have pre-existing immunity?
BMJ 2020; 370 doi: https://doi.org/10.1136/bmj.m3563 (Published 17 September 2020)Cite this as: BMJ 2020;370:m3563https://www.bmj.com/content/370/bmj.m3563
Not so novel coronavirus?
At least six studies have reported T cell reactivity against SARS-CoV-2 in 20% to 50% of people with no known exposure to the virus.5678910
In a study of donor blood specimens obtained in the US between 2015 and 2018, 50% displayed various forms of T cell reactivity to SARS-CoV-2.511 A similar study that used specimens from the Netherlands reported T cell reactivity in two of 10 people who had not been exposed to the virus.7
In Germany reactive T cells were detected in a third of SARS-CoV-2 seronegative healthy donors (23 of 68). In Singapore a team analysed specimens taken from people with no contact or personal history of SARS or covid-19; 12 of 26 specimens taken before July 2019 showed reactivity to SARS-CoV-2, as did seven of 11 from people who were seronegative against the virus.8 Reactivity was also discovered in the UK and Sweden.6910
T cell studies have received scant media attention, in contrast to research on antibodies, which seem to dominate the news (probably, says Buggert, because antibodies are easier, faster, and cheaper to study than T cells). Two recent studies reported that naturally acquired antibodies to SARS-CoV-2 begin to wane after just 2-3 months, fuelling speculation in the lay press about repeat infections.282930
But T cell studies allow for a substantially different, more optimistic, interpretation. In the Singapore study, for example, SARS-CoV-1 reactive T cells were found in SARS patients 17 years after infection. “Our findings also raise the possibility that long lasting T cells generated after infection with related viruses may be able to protect against, or modify the pathology caused by, infection with SARS-CoV-2,”8 the investigators wrote.
T cell studies may also help shed light on other mysteries of covid-19, such as why children have been surprisingly spared the brunt of the pandemic, why it affects people differently, and the high rate of asymptomatic infections in children and young adults.
T cells could be a key factor that explains why places like New York, London, and Stockholm seem to have experienced a wave of infections and no subsequent resurgence. This would be because protective levels of immunity, not measurable through serology alone but instead the result of a combination of pre-existing and newly formed immune responses, could now exist in the population, preventing an epidemic rise in new infections.
Theoretically, the placebo arm of a covid-19 vaccine trial could provide a straightforward way to carry out such a study, by comparing the clinical outcomes of people with versus those without pre-existing T cell reactivity to SARS-CoV-2. A review by The BMJ of all primary and secondary outcome measures being studied in the two large ongoing, placebo controlled phase III trials, however, suggests that no such analysis is being done.3334
Could pre-existing immunity be more protective than future vaccines? Without studying the question, we won’t know.
Research establishments including Yale found that in mild or asymptomatic cases, many T-cells are produced. These were highly varied, responding not just to parts of the Spike, S protein or Receptor Binding Domain but to many other parts of the virus. Notably, in these mild cases there were few or no detectable antibodies. Conversely, the severely ill produced few T-cells with less variety but had plenty of antibodies. What is also of interest is that men produced fewer T-cells than women, and unlike women, their T-cell response reduced with age.
Single-Cell Omics Reveals Dyssynchrony of the Innate and Adaptive Immune System in Progressive COVID-19
A dysregulated immune response against the SARS-CoV-2 virus plays a critical role in severe COVID-19. However, the molecular and cellular mechanisms by which the virus causes lethal immunopathology are poorly understood.https://www.medrxiv.org/content/10.1101/2020.07.16.20153437v1
Reevaluate your nutrition strategy amid COVID-19, doctors say
"Several research studies have discovered a correlation between high blood sugar levels and immune dysfunction. High blood sugar prevents critical immune cells called neutrophils from releasing disease-fighting proteins and enzymes stored within the cells. It also inhibits “phagocytosis,” a process where immune cells engulf foreign pathogenic particles that dare to cross their paths. Neutrophil and phagocytosis are key for human health, as they allow the body to fight various infections, including respiratory viruses. "
from
http://www.thehealthyhomeeconomist.com/best-vegetables-boosting-immunity/
I've been doing these things for myself and my family for over 40 years and kept them out of the hospital, all are healthy and still living today.
Thank you all for sharing. We gotta help one another
https://draxe.com/nutrition/antiviral-herbs/
https://draxe.com/health/how-to-boost-your-immune-system/
The fact is Isolation weakens your immune system. Sitting on your couch all day weakens your immune system. Excessive amounts of hand sanitizer weaken your immune system by killing your microboime. Lack of fresh air and sunshine weakens your immune system. Lack of exposure to germs weakens your immune system. [Yes, use common sense and proper hygiene.] Sedentary lifestyle weakens your immune system. It doesn’t take long either. Sugar also weakens your immune system. Lack of vitamins and nourishment weakens your immune system. These are facts. This is human biology 101. Our bodies need to be in harmony and balance with the bacteria and virus in nature to build immunity. This is known as the human virome which is made up of 380 trillion virus we have been exposed to over the past 200,000 years. Our immune system needs to keep up and be in balance with the ever changing/mutating germs. Do you put your faith in the spoonful of medicine that has been around for 2 months or the power that has been animating this earth for eons?
-Nicholas Froehling
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