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The Autism Discussion

Yep, just another fraction of the post. But, there are some great resources here for you to develop your OWN thoughts, beliefs, and practices. 



Autism

Since 1990, it's become an epidemic. 
      Even though the labeling of an epidemic has been swept under the rug. 
  • CDC 
    • Avg state increases of  1700% (only looking at 15% of total cases) 
      • Prevalence is equal across states, races, ethnicities, class, etc.  
      • 1:10,000 in the 1970's
      • 1 in 68  identified with ASD (by 2014) -->most commonly cited number. At the moment... 
      • Now 1:35---> according to some sources
        • 1 in 42 boys
      • 1:2 before 2040  (Look up Stephanie Seneff)  If we keep going at the rate we are.. it may be before 2030.  
    • Link to MMR? 
      • Glutamate 
      • Connection drawn by Dr. Wakefield
        • At the time of his first 'retracted' paper, he was merely drawing an observational connection and calling for further research.  
        • Disruption of Gut/brain axis 
      • In conjunction with acetaminophen that can be toxic, especially with children as they can't metabolize the meds.  Glutathione production is severely stunted, so detoxing from the toxins that enter directly into systemic circulation cannot be sufficiently eradicated from the body. Stored in tissues (especially fat) 
      • Development of blood/brain barrier has not yet formed.  The passage of toxins injected directly into the body/blood transfers directly into the brain.  
      • Glyphosate multiplies and enhances the toxicity by chelating with metals and minerals, including aluminum and glutamate.  Along with destroying the gut barrier, as well as the blood brain barrier. 
        • Al usually has a strong positive charge that would normally be kept in the gut, but in this cage, it acts like a neutral molecule that can get past the gut barrier.  Glyphosate has also been shown to perforate the gut lining, thus bringing itself, along with other chelated molecules, into circulation. 
        • Pineal gland may be one of the most vulnerable as it is located outside of the blood-brain barrier and has been shown to contain 2x the amount of aluminum as the rest of the CNS. Disorders of the pineal gland (melatonin- glyphosate disrupts the Shikamate pathway of our gut bacteria that produces tryptophan that is a precursor to melatonin, seratonin, and melanin) obviously lead to sleep disorders (amongst others), and conditions linked with sleep disorders include many neurodegenerative disorders-MS, Alzheimers, Parkinsons, etc
    •  2011 Nov;105(11):1489-99. doi: 10.1016/j.jinorgbio.2011.08.008. Epub 2011 Aug 23.

      Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?



    • https://www.ncbi.nlm.nih.gov/pubmed/22099159 

ICAN

AUTISM & ALUMINUM ADJUVANTS IN VACCINES 
How Aluminum Adjuvants in Vaccines Can Cause Autism

Did Chinese scientists find autism’s missing puzzle piece?



 1998 Oct;89(1):105-8.

Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism.



Detection of plasma autoantibodies to brain tissue in young children with and without autism spectrum disorders

  • Genetic component is minimal"
    • "Currently, 10–20% of cases are associated with defined mutations, genetic syndromes, or de novo copy number variations, and further cases will likely be attributable to genetic variations upon further study (Abrahams and Geschwind, 2008). However, none of the variations discovered so far consistently results in an individual developing an ASD, suggesting other factors must be involved (Abrahams and Geschwind, 2008)."


CDC--> you're fired

Listen to Ben Swann and his Investigative Research: History behind MMR, other vaccines, from Wakefield to the CDC covering their tails. 
https://www.facebook.com/BenSwannRealityCheck/videos/1043476625717287/

Vaccines and Pregnancy: The Criminal Conspiracy to Create Autism

https://thehomestead.guru/vaccines-pregnancy/
  • Some great info/studies here. 
    • to make you go hmmmmmm... WTF

How vaccines affect the microglial cells in your brain--causing chronic inflammation and subsequent destruction. 
http://drbogner.com/vaccine-mechanisms-in-autism/
  • M1 activated microglia are necessary for acute situations with antigens present. 
    • "Certain adjuvants in vaccines are powerful activators of brain microglia. Heavy metals like aluminum keep microglia in the activated state longer and make it difficult to switch into the anti-inflammatory state [23]. Aluminum is currently contained in DTaP, polio and Hib, Hepatitis A & B, Gardasil, Influenza and Pneumococcus [140]. As you will find out soon, there is an unreported chemical in vaccines that was found that prevents the microglia from flipping out of the inflammatory state. This chemical is called glyphosate [more below]."
    • Vaccines prevent the necessary activation/release of M2 microglial cells 
    • "Similar to the M1 state, the beneficial M2 state releases anti-inflammatory cytokines and growth factors that participate in a wide range of biological responses, including increased neurogenesis and development as well as modulation of inflammation and immune responses, [104], [105], [106], [107], [108], [109]. They literally hold the keys for regulation of brain homeostasis [68]."

  • A case series of children with apparent mercury toxic encephalopathies manifesting with clinical symptoms of regressive autistic disorders.

    • http://www.ncbi.nlm.nih.gov/pubmed/17454560
      • Dec. Glutathione pathways 
      • Excessive amounts of mercury with chelation challenge
      • Elevated levels of androgens
      • Only exposure to known levels of mercury was from mercury/thimerosal containing vaccines
      • Significant correlation with mercury induced encephalopathies early on in development, which regressed to ASD. 
    • http://www.ncbi.nlm.nih.gov/pubmed/16264412

      • Mercury and autism: accelerating evidence?


      • Found that autistic children had a higher mercury exposure during pregnancy due to maternal dental amalgam and thimerosal-containing immunoglobulin shots. It was hypothesized that children with autism have a decreased detoxification capacity due to genetic polymorphism. In vitro, mercury and thimerosal in levels found several days after vaccination inhibit methionine synthetase (MS) by 50%. Normal function of MS is crucial in biochemical steps necessary for brain development, attention and production of glutathione, an important antioxidative and detoxifying agent. Repetitive doses of thimerosal leads to neurobehavioral deteriorations in autoimmune susceptible mice, increased oxidative stress and decreased intracellular levels of glutathione in vitro. Subsequently, autistic children have significantly decreased level of reduced glutathione. Promising treatments of autism involve detoxification of mercury, and supplementation of deficient metabolites.
        A case series of children with apparent mercury toxic encephalopathies manifesting with clinical symptoms of regressive autistic disorders.
        http://www.ncbi.nlm.nih.gov/pubmed/17454560 
. 2013; 2: 25.
Published online 2013 Dec 19. doi:  10.1186/2047-9158-2-25
PMCID: PMC3878266


Real-Life Data Show that the CDC Vaccine Schedule is Causing Harm


The practice data showed the following:
  • One case of autism in the unvaccinated group—a rate of 1 in 715.
  • Six cases of autism in the partially vaccinated group—a rate of 1 in 438.
  • In comparison, government data from the National Health Interview Survey (NHIS) show a diagnosed autism rate of 1 in 45 children (aged 3-17 years) as of 2014 and, by 2016, a rate of 1 in 36.
In an interview with Del Bigtree on the show HighWire, Dr. Thomas put his practice data in a wider context, noting that if California followed the modified vaccine schedule, it would spare about 9,000 cases of autism annually. At a national level, the slower schedule would prevent about 90,000 cases of autism annually. Dr. Thomas also explained that the consultant’s findings validate his own waiting room observations of an “incredibly healthy” patient population. On the other hand, he speculated that the autism rate in the unvaccinated group might have been even lower—perhaps 1 in 1,000 or less—if his unvaccinated group came from a low-risk patient population

A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States


Thimerosal Exposure and the Role of Sulfation Chemistry and Thiol Availability in Autism

  • Immunological Findings in Autism 
    •  http://www.ncbi.nlm.nih.gov/pubmed/16512356
    • Depressed cell-mediated immune response due to reduced CD4 cell count. Imbalance of Th1/Th2 receptors 
    • Depressed humoral immunity which is noted with a decreased IgA, leading to poor gut/immune protection. 
    • Autoimmune mechanisms supported through other studies (towards brain tissue) 
    • Activation of astrocytes and microglial cells are inhibited by mercury ions. Signs of neural edema. 
    • Apoptotic signaling pathways disrupted as well
    • Down regulation of MHC class II receptors 
    • Constant elevation of certain classes of cytokines and chemokines 
    • Autoantibodies (IgG isotype) to neuron-axon filament protein (NAFP) and glial fibrillary acidic protein (GFAP) are significantly increased in autistic patients
    • MMR antibodies are significantly higher in autistic children
    • Cytokine alteration of TNF 
    • •Autism costs a family $60,000 a year on average
      •Autism receives less than 5% of the research funding of many less prevalent childhood diseases

  • Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism.

    • http://www.ncbi.nlm.nih.gov/pubmed/9756729
    • This study is the first to report an association between virus serology and brain autoantibody in autism; it supports the hypothesis that a virus-induced autoimmune response may play a causal role in autism.

  • Infections, toxic chemicals and dietary peptides binding to lymphocyte receptors and tissue enzymes are major instigators of autoimmunity in autism.

    • How interesting...
      •  We, therefore, propose that bacterial antigens (SK), dietary peptides (gliadin, casein) and Thimerosal (ethyl mercury) in individuals with pre-disposing HLA molecules, bind to CD26 or CD69 and induce antibodies against these molecules. In conclusion, this study is apparently the first to demonstrate that dietary peptides, bacterial toxins and xenobiotics bind to lymphocyte receptors and/or tissue enzymes, resulting in autoimmune reaction in children with autism.
      • http://www.ncbi.nlm.nih.gov/pubmed/14611720
  • Autism: a novel form of mercury poisoning
 2017 Jul;42:18-24. doi: 10.1016/j.jtemb.2017.03.005. Epub 2017 Mar 9.

Increased risk for an atypical autism diagnosis following Thimerosal-containing vaccine exposure in the United States: A prospective longitudinal case-control study in the Vaccine Safety Datalink

The Environmental Influences

It's VERY difficult to attribute ANY condition to one particular CAUSE.  Which is an uncomfortable notion to many as we are use to 'simple' fixes, such as taking medications to mask illness and disease. To say that autism is caused by vaccines is nearly impossible to assess as there are many environmental triggers that could possibly be linked to 
http://kinseimindbody.com/synergistic-destruction-how-vaccines-and-gmos-converge-to-fuel-autism-and-neurodegenerative-conditions/



Impact of environmental factors on the prevalence of autistic disorder after 1979

  • "The aim of this study was to investigate a previously overlooked, universally introduced environmental factor, fetal and retroviral contaminants in childhood vaccines, absent prior to change points (CPs) in autistic disorder (AD) prevalence with subsequent dose-effect evidence and known pathologic mechanisms of action.  Worldwide population based cohort study was used for the design of this study. The United States, Western Australia, United Kingdom and Denmark settings were used. All live born infants who later developed autistic disorder delivered after 1 January 1970, whose redacted vaccination and autistic disorder diagnosis information is publicly available in databases maintained by the US Federal Government, Western Australia, UK, and Denmark. "
    • " The children vaccinated with MMRII, Varicella and Hepatitis A vaccines varied from 19 to 35 months of age at the time of vaccination. Autistic disorder birth year change points were identified as 1980.9, 1988.4 and 1996 for the US, 1987 for UK, 1990.4 for Western Australia, and 1987.5 for Denmark. Change points in these countries corresponded to introduction of or increased doses of human fetal cell line-manufactured vaccines, while no relationship was found between paternal age or Diagnostic and Statistical Manual (DSM) revisions and autistic disorder diagnosis. Further, linear regression revealed that Varicella and Hepatitis A immunization coverage was significantly correlated to autistic disorder cases. R software was used to calculate change points. Autistic disorder change points years are coincident with introduction of vaccines manufactured using human fetal cell lines, containing fetal and retroviral contaminants, into childhood vaccine regimens. This pattern was repeated in the US, UK, Western Australia and Denmark. Thus, rising autistic disorder prevalence is directly related to vaccines manufactured utilizing human fetal cells."

  • Hepatitis B vaccination of male neonates and autism diagnosis, NHIS 1997-2002

    • http://www.ncbi.nlm.nih.gov/pubmed/21058170
    • 'Findings suggest that U.S. male neonates vaccinated with the hepatitis B vaccine prior to 1999 (from vaccination record) had a threefold higher risk for parental report of autism diagnosis compared to boys not vaccinated as neonates during that same time period. Nonwhite boys bore a greater risk.Findings suggest that U.S. male neonates vaccinated with the hepatitis B vaccine prior to 1999 (from vaccination record) had a threefold higher risk for parental report of autism diagnosis compared to boys not vaccinated as neonates during that same time period. Nonwhite boys bore a greater risk.'
    • http://www.ncbi.nlm.nih.gov/pubmed/22015977

 2011 Dec;77(6):940-7. doi: 10.1016/j.mehy.2011.08.019. Epub 2011 Oct 10.

Hypothesis: conjugate vaccines may predispose children to autism spectrum disorders.



Head Lag a Red Flag?
  • https://www.autismspeaks.org/science/science-news/head-lag-red-flag

    Yes, There Is an Autism Epidemic

    Interesting insight.  
    http://historynewsnetwork.org/article/161992

    Number of California students classified as autistic jumps for 14th consecutive year

    • The number of autistic students statewide has risen by between 5,000 and 7,000 every year for a decade.
    • 14k to 90k.  2001-2016.

    A cleanroom sleeping environment's impact on markers of oxidative stress, immune dysregulation, and behavior in children with autism spectrum disorders.


     2004 Nov-Dec;23(6):369-76.

    Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis.



    PhD Scientist and Biochemist Reveals Hidden CDC Documents Showing Thimerosal In Vaccines Increase Neurologic Disorders

    Former Science Chief

    • MMR fears coming true
      • http://www.dailymail.co.uk/health/article-376203/Former-science-chief-MMR-fears-coming-true.html
      • " Dr Peter Fletcher, who was Chief Scientific Officer at the Department of Health, said if it is proven that the jab causes autism, "the refusal by governments to evaluate the risks properly will make this one of the greatest scandals in medical history". He added that after agreeing to be an expert witness on drug-safety trials for parents' lawyers, he had received and studied thousands of documents relating to the case which he believed the public had a right to see. He said he has seen a "steady accumulation of evidence" from scientists worldwide that the measles, mumps and rubella jab is causing brain damage in certain children. But he added: "There are very powerful people in positions of great authority in Britain and elsewhere who have staked their reputations and careers on the safety of MMR and they are willing to do almost anything to protect themselves."
    Evidence of Harm

    • Autistic children have been found to have low levels of secretin, which is naturally found in the human body and is found in the liver, pancreas, brain and upper GI.  
    • One of its functions is to stimulate the pancreas to release bicarbonate. Helps the GI system  with the absorption of food by  neutralizing stomach acid-allowing specific enzymes to break down food so that it can be absorbed.  Autistic children are deficient in neurotransmitters such as seratonin, which 95% of seratonin is produced in the gut. 

     Acetaminophen, 

    Did Acetaminophen Provoke the Autism Epidemic?
    http://www.autismstudies.net/Acetaminophen_files/Did%20acetaminophen%20provoke%20epidemic%3Fpdf.pdf


    Acetaminophen during pregnancy can inhibit masculinity

    • "Previous studies have shown the paracetamol can inhibit the development of the male sex hormone testosterone in male foetuses, thus increasing the risk of malformation of the testicles in infants. But a reduced level of testosterone at the fetal stage is also significant for the behaviours of adult males, says Ph.D. David Møbjerg Kristensen,"
    • " In 2016, the researchers published a study showing that female mice had fewer eggs in their ovaries if their mothers had had paracetamol during pregnancy. This led to the mice becoming infertile more quickly"

    Vaccines and autism: a new scientific review



    Theoretical aspects of autism: Causes—A review

    http://www.tandfonline.com/doi/full/10.3109/1547691X.2010.545086

    • "In general, the autism increase is not considered a result of reclassification (Sullivan, 2005Sullivan, M. G. 2005. Autism increase not a result of reclassification. Clin. Psychiat. News. May, p. 68. [Google Scholar]). Although autism diagnoses have risen, there are no corresponding decreases in other diagnostic categories."
    • "Data from a worldwide composite of studies show that an increase in cumulative incidence began about 1988–1990 (McDonald and Paul, 2010McDonald, M. E., and Paul, J. F. 2010. Timing of increased autistic disorder cumulative incidence. Environ. Sci. Technol. 44:2112–2118. [Google Scholar]). The new version of the measles, mumps, rubella vaccine (i.e., MMR II) that did not contain Thimerosal was introduced in 1979. By 1983, only the new version was available. Autism in the United States spiked dramatically between 1983 and 1990 from 4–5/10,000 to 1/500. In 1988, two doses of MMR II were recommended to immunize those individuals who did not respond to the first injection. A spike of incidence of autism accompanied the addition of the second dose of MMR II. Also, in 1988, MMR II was used in the United Kingdom, which reported a dramatic increase in prevalence of autism to 1/64 (noted above). Canada, Denmark, and Japan also reported dramatic increases in prevalence of autism. It is important to note that unlike the former MMR, the rubella component of MMR II was propagated in a human cell line derived from embryonic lung tissue (Merck and Co., Inc., 2010Merck & Co., Inc. 2010. M-M-R® II (Measles, Mumps, and Rubella Virus Vaccine Live). 9912201. [Google Scholar]). The MMR II vaccine is contaminated with human DNA from the cell line. This human DNA could be the cause of the spikes in incidence. An additional increased spike in incidence of autism occurred in 1995 when the chicken pox vaccine was grown in human fetal tissue (Merck and Co., Inc., 2001Merck & Co., Inc. 2001. VARIVAX® (Varicella Virus Vaccine Live). 9904702. [Google Scholar]; Breuer, 2003Breuer, J. 2003. Live attenuated vaccine for the prevention of varicella-zoster virus infection: does it work, is it safe and do we really need it in the UK? J. Med. Microbiol. 52:1–3. [Google Scholar])"
    • "The immune system is particularly sensitive at 2 months of age. Although specific immune functions, governed by B- and T-lymphocytes, are competent in the newborn (Solomon, 1971Solomon, J. B. (Ed). 1971. Foetal and Neonatal Immunology. Amsterdam: Elsevier Publishing Co. [Google Scholar]), the polymorphonuclear cells are less in number than the lymphocytes in the peripheral blood (Diem, 1962Diem, K. (Ed). 1962. Documenta Geigy Scientific Tables. Edition 6., Ardsley, NY: Geigy Pharmaceuticals. [Google Scholar]). Also, the phagocytic cells and complement system of a newborn are decreased in function (Xanthou et al., 1975Xanthou, M., Valassi-Adam, E., Kintsonidou, E., and Matsaniotis, N. 1975. Phagocytosis and killing ability of Candida albicans by blood leucocytes of healthy term and preterm babies. Arch. Dis. Child. 50:72–75. [Google Scholar]; Madden et al., 1989Madden, N. P., Levinsky, R. J., Bayston, R., Harvey, B., Turner, M. W., and Spitz, L. 1989. Surgery, sepsis, and nonspecific immune function in neonates. J. Pediatr. Surg. 24:562–566. [Google Scholar]). Thus, the immune system of an infant is compromised at 2 months. A challenge by so many vaccines while the immune system is compromised might contribute to an onset of autism."
    • "The vaccine organism itself could be a culprit. For example, one hypothesis of the cause of autism is that the pertussis toxin in the DPT vaccine causes a separation of the G-alpha protein from retinoid receptors in genetically at-risk children (Farfel et al., 1999Farfel, Z., Bourne, H. R., and Iiri, T. 1999. The expanding spectrum of G protein diseases. N. Engl. J. Med. 340:1012–1020.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar]; Megson, 2000Megson, M. N. 2000. Is autism a G-alpha protein defect reversible with natural vitamin A? Med. Hypotheses. 54:979–983. [Google Scholar]). The pertussis toxin creates a chronic autoimmune monocytic infiltration of the gut mucosa lamina propia and may disconnect the G-alpha protein pathways, leaving some G-alpha-modulated pathways unopposed. In turn, the non-specific branch of the immune system is turned on and, without retinoid switching, cannot be down regulated."
    • "Another organism of suspect is the live measles virus. When the measles vaccine is given, it depletes the children of their existing supply of Vitamin A, which negatively impacts the retinoid receptors, accounting for the distorted vision in autistic individuals"
    • Thimerosal
      • There is evidence that Thimerosal (which is 49% ethyl mercury) is indeed harmful. Since the 1930s, Thimerosal has been extensively used as an antibacterial agent in vaccines (Geier et al., 2007Geier, D. A., Sykes, L. K., and Geier, M. R. 2007. A review of Thimerosal (Merthiolate) and its ethylmercury breakdown product: specific historical considerations regarding safety and effectiveness. J. Toxicol. Environ. Health. B. Crit. Rev. 10:575–596.[Taylor & Francis Online], [Web of Science ®], [Google Scholar]). Thimerosal has been implicated as a cause of autism. Not only is every major symptom of autism documented in cases of mercury poisoning but also biological abnormalities in autism are very similar to the side effects of mercury poisoning itself (Bernard et al., 2001Bernard, S., Enayati, A., Redwood, L., Roger, H., and Binstock, T. 2001. Autism: a novel form of mercury poisoning. Med. Hypotheses. 56:462–471.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar]): these include psychiatric disturbances (e.g., impairments in sociality, stereotypic behaviors, depression, anxiety disorder, and neuroses), increased incidences of allergies and asthma, increases in the presence of IgG autoantibodies against brain and myelin basic proteins, reductions in natural killer cell function, and increases in neopterin levels (indicative of immune activation). Autistic brains show neurotransmitter irregularities that are virtually identical to those arising from mercury exposure, i.e., changes in serotonin and dopamine concentrations, elevated epinephrine and norepinephrine levels in the plasma and brain, elevated serum glutamate levels, and an acetylcholine deficiency in the hippocampus (Bernard et al., 2001Bernard, S., Enayati, A., Redwood, L., Roger, H., and Binstock, T. 2001. Autism: a novel form of mercury poisoning. Med. Hypotheses. 56:462–471.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar]). Due to the extensive parallels between autism and mercury poisoning, the likelihood of a causal relationship is great. More evidence linking autism with mercury poisoning is the timing of inclusion of Thimerosal in vaccines in the 1930s closely preceding the discovery of autism in 1943 (Kanner, 1943Kanner, L. 1943. Autistic disturbances of affective contact. Nervous Child 2:217–250. [Google Scholar]).
    • "Supporting this relationship are reports documenting that heavy metals are increased in the blood and urine of autistic subjects (Bernard et al., 2001Bernard, S., Enayati, A., Redwood, L., Roger, H., and Binstock, T. 2001. Autism: a novel form of mercury poisoning. Med. Hypotheses. 56:462–471.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar]; Walsh et al., 2001Walsh, W. J., Usman, A., and Tarpey, J. 2001. Disordered metal metabolism in a large autism population. Am. Psychiatric Association Meeting May, New Orleans. [Google Scholar]). Walsh et al. (2001Walsh, W. J., Usman, A., and Tarpey, J. 2001. Disordered metal metabolism in a large autism population. Am. Psychiatric Association Meeting May, New Orleans. [Google Scholar]) studied blood and urine from 503 patients with autism, Asperger’s syndrome, or atypical autism, and compared their results to samples from neurotypical controls. The analyses revealed that 85% of the patients exhibited severely elevated Cu:Zn ratios and 99% showed evidence of a metal-metabolism disorder, suggesting defective metallothionein. Defective metallothionein might be responsible for the greater amount of blood mercury found in autistic children compared to neurotypical controls (Desoto and Hitlan, 2007; Geier et al., 2010Geier, D. A., Audhya, T., Kern, J. K., and Geier, M. R. 2010. Blood mercury levels in autism spectrum disorder: Is there a threshold level? Acta Neurobiol. Exp. (Wars). 70:177–186. [Google Scholar]). Metallothionein plays an important role in the development and continued function of the immune response, in neuronal development, and in the detoxification of heavy metals. "
    • "Mast cells are involved in allergic reactions, and also in inflammation, and innate and acquired immunity. Autistic individuals have a 10-fold greater number of hyperactive mast cells in most tissues. Mercury stimulates vascular endothelial growth factor and interleukin (IL)-6 release from mast cells. These mediators could disrupt the blood–brain barrier and cause brain inflammation (Kempuraj et al., 2010Kempuraj, D., Asadi, S., Zhang, B., Manola, A., Hogan, J., Peterson, E., and Theoharides, T.C. 2010. Mercury induces inflammatory mediator release from human mast cells. J. Neuroinflammation. 7:20. [Google Scholar]). "
    • AGE of Parents 
    • "mitochondrial dysfunction in autistic individuals without the classic features associated with mitochondrial disease. Mitochondrial dysfunction is thought to be caused by environmental toxins and could contribute to the altered energy metabolism in the brains of children with autism (Chugani et al., 1999Chugani, D. C., Muzik, O., Behen, M., Rothermel, R., Janisse, J. J., Lee, J., and Chugani, H.T.. 1999. Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children. Ann. Neurol. 45:287–295.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar]). "
    • "Organophosphate pesticides, at levels common among the United States children, may contribute to ADHD prevalence (Bouchard et al., 2010Bouchard, M. F., Bellinger, D. C., Wright, R. O., and Weisskopf, M. G. 2010. Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides. Pediatrics. 125:e1270–e1277.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar]). Cross-sectional data from the National Health and Nutrition Examination Survey (2002–2004) were available from 1139 children between 8–15 years of age. Exposure to the pesticides could be prenatal, direct, or from food, drinking water or residential pesticide use. The data prove an association between urinary dimethylalkylphosphate (DMAP) metabolic concentrations (indicative of exposure to dimethyl-containing organophosphate pesticides) and increased odds of ADHD. A primary action of organophosphates is inhibition of acetyl cholinesterase (Sultatos, 1994Sultatos, L. G. 1994. Mammalian toxicology of organophosphorus pesticides. J. Toxicol. Environ. Health. 43:271–289.[Taylor & Francis Online], [Web of Science ®], [Google Scholar]). Disruptions in cholinergic signaling are thought to occur in ADHD (Nedic et al., 2010Nedic, G., Pivac, N., Hercigonja, D. K., Jovancevic, M., Curkovic, K. D., and Muck-Seler, D. 2010. Platelet monoamine oxidase activity in children with attention-deficit/hyperactivity disorder. Psychiatry Res. 175:252–255. [Google Scholar]). In addition, Chlorpyrifos, an organophosphate insecticide widely used until a few years ago to control insects in schools and homes and still used extensively in agriculture, is a developmental neurotoxicant (Landrigan, 2010Landrigan, P. J. 2010. What causes autism? Exploring the environmental contribution. Curr. Opin. Pediatr. 22:219–225.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar])."
    • "GSH is decreased in the plasma of autistic subjects (Geier and Geier, 2006bGeier, D. A., and Geier, M. R. 2006. A clinical and laboratory evaluation of methionine cycle-transsulfuration and androgen pathway markers in children with autistic disorders. Horm. Res. 66:182–188. [Google Scholar]; Geier et al., 2009Geier, D. A., Kern, J. K., Garver, C. R., Adams, J. B., Audhya, T., Nataf, R., and Geier, M. R. 2009. Biomarkers of environmental toxicity and susceptibility in autism. J. Neurol. Sci. 280:101–108.[CrossRef], [Google Scholar]). In addition, GSH plays a major role in methylation and is intimately involved in detoxification processes."
    • "Porphyrins, derivatives of the heme synthesis pathway and used as measures of xenobiotic exposure, have been documented to be increased in the urine of autistic individuals (Geier and Geier, 2006aGeier, D. A., and Geier, M. R. 2006. A prospective assessment of porphyrins in autistic disorders: a potential marker for heavy metal exposure. Neurotox. Res. 10:57–64.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar]; Nataf et al., 2006Nataf, R., Skorupka, C., Amet, L., Lam, A., Springbett, A., and Lathe, R. 2006. Porphyrinuria in childhood autistic disorder: implications for environmental toxicity. Toxicol. Appl. Pharmacol. 214:99–108.[CrossRef], [PubMed], [Web of Science ®], [Google Scholar])."

    Antidepressant Use During Pregnancy and the Risk of Autism Spectrum Disorder in Children.



    Avg time of parent 'concern' over autism Dx to actual clinical Dx is 22mo... 
    by this time.. would most people would not make the link, or easily write it off.  But, parents are not dumb; when your own child regresses into an autistic state weeks, days, moments after their onslaught of vaccinations... it's pretty easy to make that correlation.


    Autism Spectrum Disorder Linked To Mitochondrial DNA Mutations


    Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis



    Interesting new research towards a 'cure'

      Link Explained by Dr. Seneff


      along with the synergistic effect of glyphosate:  https://www.youtube.com/watch?v=6zOlGf_MWsg


      Undeniable link to glyphosate:

      • Nutritional deficiencies, as glyphosate immobilizes certain nutrients and alters the nutritional composition of the treated crop
        Disruption of the biosynthesis of aromatic amino acids (these are essential amino acids not produced in your body that must be supplied via your diet)
        Increased toxin exposure (this includes high levels of glyphosate and formaldehyde in the food itself)
        Impairment of sulfate transport and sulfur metabolism; sulfate deficiency
        Systemic toxicity—a side effect of extreme disruption of microbial function throughout your body; beneficial microbes in particular, allowing for overgrowth of pathogens
        Gut dysbiosis (imbalances in gut bacteria, inflammation, leaky gut, food allergies such as gluten intolerance)
        Enhancement of damaging effects of other food-borne chemical residues and environmental toxins as a result of glyphosate shutting down the function of detoxifying enzymes
        Creation of ammonia (a byproduct created when certain microbes break down glyphosate), which can lead to brain inflammation associated with autism and Alzheimer's disease


      Disrupted Gut

      Five Scientific Facts: Links between Autism and Vaccines?

      Role of Microglia 


      Sooo... they have NO idea what the CAUSE is... 
      http://www.ncbi.nlm.nih.gov/pubmed/15121991



      Vaccines linked to mental disorders by Yale study



      http://yaledailynews.com/blog/2017/02/21/vaccines-linked-to-mental-disorders-by-yale-study/




      Sooooooo MORE RESEARCH to dive into:


      Vaccines and autism
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878266/
      http://www.ncbi.nlm.nih.gov/pubmed/21623535
      http://www.ncbi.nlm.nih.gov/pubmed/25377033
      http://www.ncbi.nlm.nih.gov/pubmed/24995277
      http://www.ncbi.nlm.nih.gov/pubmed/12145534
      http://www.ncbi.nlm.nih.gov/pubmed/21058170
      http://www.ncbi.nlm.nih.gov/pubmed/22099159
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364648/
      http://www.ncbi.nlm.nih.gov/pubmed/17454560
      http://www.ncbi.nlm.nih.gov/pubmed/19106436
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774468/
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697751/
      http://www.ncbi.nlm.nih.gov/pubmed/21299355
      http://www.ncbi.nlm.nih.gov/pubmed/21907498
      http://www.ncbi.nlm.nih.gov/pubmed/11339848
      http://www.ncbi.nlm.nih.gov/pubmed/17674242
      http://www.ncbi.nlm.nih.gov/pubmed/21993250
      http://www.ncbi.nlm.nih.gov/pubmed/15780490
      http://www.ncbi.nlm.nih.gov/pubmed/12933322
      http://www.ncbi.nlm.nih.gov/pubmed/16870260
      http://www.ncbi.nlm.nih.gov/pubmed/19043938
      http://www.ncbi.nlm.nih.gov/pubmed/12142947
      http://www.ncbi.nlm.nih.gov/pubmed/24675092
      http://www.ncbi.nlm.nih.gov/pubmed/25198681
      PLUS:
      Autism
      Genetic markers and toxins in vaccines link to autism
      http://www.ncbi.nlm.nih.gov/pubmed/23576057
      Heavy Metals in Hair Samples from Severely Autistic Children
      http://www.mdpi.com/1660-4601/9/12/4486
      Conjugate Vaccines may predispose children to autism disorders
      http://www.ncbi.nlm.nih.gov/pubmed/23576057
      Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism.
      http://www.ncbi.nlm.nih.gov/pubmed/12145534
      A positive association found between autism prevalence and childhood vaccination uptake across the U.S.
      http://www.ncbi.nlm.nih.gov/pubmed/21623535
      Causal relationship between vaccine induced immunity and autism
      http://www.ncbi.nlm.nih.gov/pubmed/12849883
      Subtle DNA changes and the overuse of vaccines in autism
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364648/
      Vaccine and Autism- a New Scientific Review
      http://www.cbsnews.com/.../vaccines-and-autism-a-new.../
      Summary of previous Journal of Immunology
      http://danmurphydc.com/.../AR-10-12-rata-AUTISM-VACCINE.pdf
      Autism and Resulting Medical Conditions: 3 mg pdf. Do not click on phone
      http://www.tacanow.org/.../09/autism-studies-april-2008.pdf .
      Mercury toxic encephalopathy manifesting with clinical symptoms of regressive autistic disorders. http://www.ncbi.nlm.nih.gov/pubmed/17454560
      Relation of mercury to high autism rates in boys
      http://www.ncbi.nlm.nih.gov/pubmed/16264412
      Elevated levels of measles in children with Autism
      http://www.ncbi.nlm.nih.gov/pubmed/12849883
      Abnormal MMR antibodies in children with autism
      http://www.ncbi.nlm.nih.gov/pubmed/12145534
      Tylenol, MMR and Autism - A parent survey study
      http://www.ncbi.nlm.nih.gov/pubmed/18445737
      A Positive Association found between Autism Prevalence and Childhood Vaccination
      http://www.ingentaconnect.com/.../00000014/art00002...
      Peer reviewed study on fetal cell contamination with retro virus associated with autism and cancer
      http://www.globalresearch.ca/new-study-in-journal.../5402912
      Autism and mercury poisoning
      http://www.ncbi.nlm.nih.gov/pubmed/11339848
      Hypothesis: conjugate vaccines may predispose children to autism spectrum disorders
      http://www.ncbi.nlm.nih.gov/pubmed/21993250
      Rise in autism coincides with rise in vaccines
      http://www.ncbi.nlm.nih.gov/pubmed/21623535








      Pretty sad this is the 'other' side's viewpoint..  Yes... keep trying to rationalize things, it's not helping.
      https://www.scientificamerican.com/article/the-real-reasons-autism-rates-are-up-in-the-u-s/?WT.mc_id=SA_FB_MB_NEWS

      Autistic Child Improves After Chiropractic Care

      • 1)    Speech/language/communication score decreased from 23/28 to 15/28 for a 34.8% improvement.
        2)    Sociability score decreased from 28/40 to 14/40 for a 50% improvement.
        3)    Sensory/cognitive awareness decreased from 20/36 to 10/36 for a 50% improvement.
        4)    Health/physical behavior decreased from 35/75 to 24/75 for a 31.4% improvement.



      https://www.prlog.org/12651608-chiropractic-helps-child-with-autism.html

      "Research is revealing that there is a relationship between abnormalities in the spine, the nervous system, and the brain" stated Dr. Matthew McCoy, a chiropractor, public health researcher and editor of the journal that published the study. "Basic science and clinical research shows that the proper development of the brain relies heavily on proper structure and movement of the spine from an early age."
      Research has shown not only that the developing brain relies on normal structural integrity and joint movement, but that complex neurochemical communication and pathways involved in helping humans to "feel good" are tied into spinal biomechanics and their related neurological pathways.
      "It makes perfect sense when you think about it" stated McCoy. "Neurobehavioral disorders such as autism may be related to how the entire body communicates with the brain and the most critical area for this is the spine."
      • According to McCoy, "People's nervous systems need the constant stimulation of movement in order to develop and function properly. Abnormal position or movement of the spinal vertebra can develop and this can lead to nerve interference. It is this interference, called vertebral subluxations, that chiropractors correct."

      Improvement in Posture, Balance & Gait in a Child With Autism Spectrum Disorder Following Grostic Upper Cervical Chiropractic Care: A Case Report

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